anew diabetes! isnt it wonderful?
new, previously unseen type of diabetes was detected in babies from 2020 onwards
https://tekniikanmaailma.fi/jn-valmisvauvoilta-loytyi-uusi-diabetestyyppi/
a weird mutation in TMEM167A gene causes new form of diabetes
nobody knows how this mutation is formed but first discovery of it occured in late 2020
THIS SAME GENE was involved in Brazil several years ago in zikavirus babies who have microcephalia.
The gene seems to be involved both in brain and in pancreatic insulin cells.
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Professor Cnop said: “The ability to generate insulin-producing cells from stem cells has enabled us to study what is dysfunctional in the beta cells of patients with rare forms as well as other types of diabetes. This is an extraordinary model for studying disease mechanisms and testing treatments.”
This discovery shows that the TMEM167A gene is essential for the proper functioning of insulin-producing beta cells, but also for neurons, whereas it seems dispensable for other cell types. These results contribute to a better understanding of the crucial steps involved in insulin production and could shed light on research into other forms of diabetes, a disease which today affects almost 589 million people worldwide.
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